Association of Interleukin-1 Gene cluster polymorphisms with coronary slow flow phenomenon
نویسندگان
چکیده
منابع مشابه
Association of Interleukin-1 Gene cluster polymorphisms with coronary slow flow phenomenon
OBJECTIVE Coronary slow flow phenomenon (CSFP) is characterized by the decreased rate of contrast progression in epicardial coronary arteries in the absence of significant coronary stenosis. Mounting evidence has showed a significant association between inflammation and CSFP severity. This study aimed to evaluate possible associations between interleukin-1 receptor antagonist (IL-1ra) gene vari...
متن کاملInterleukin-1 gene cluster polymorphisms associated with coronary slow flow phenomenon
We found the publication “Association of Interleukin-1 Gene cluster polymorphisms with coronary slow flow phenomenon (CSFP)” (1) very interesting. Mutluer et al. (1) concluded that “IL1ß+3954 SNP mutations are significantly more common in patients with CSFP” and “It may suggest that the tendency for inflammation may contribute to the presence of this phenomenon.” In fact, based on the present s...
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Background: Slow coronary flow (SCF) is defined as a condition in which in spite of no evidence of coronary occlusion or stenosis in angiography, there is delayed pacification of the vessels after the injection of a contrast agent. There are several studies about electrocardiogram (ECG) changes in these patients, but changes like OLD MI, RBBB, LBBB, LVH and ST-T wave have not b...
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BACKGROUND AND AIMS Chronic inflammatory process plays an important role in atherothrombosis. Interleukin-1 (IL-1) is one of the key modulators of the inflammatory response and its activity is critically regulated by its receptor antagonist (IL-1Ra). A variable number tandem repeat polymorphism in intron 2 of IL-1Ra gene and a C to T single base polymorphism in the promoter of IL-1beta gene (C(...
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Background & Objective: Interleukin (IL)-10 is an important anti-inflammatory and immunomodulatory cytokine. Some authors believe that single nucleotide polymorphisms (SNP) in the promoter region of the IL-10 gene have been associated with susceptibility to HIV infection and progression to AIDS, but its role is not clearly defined yet. The present study was undertaken to evaluate the a...
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ژورنال
عنوان ژورنال: The Anatolian Journal of Cardiology
سال: 2018
ISSN: 2149-2263
DOI: 10.14744/anatoljcardiol.2017.8071